Pharmacy

1Pharmaceutical Technology II

Tecnologia Farmacêutica II

Course code:9494331

Ana Isabel Henriques Dias Fernandes Pinto

Learning outcomes of the curricular unit:

Provide students with the theoretical and practical knowledge adequate to the design, formulation, production and quality control of solutions, emulsions and suspensions, topical semi-solids, vaginal and rectal dosage forms, and the sterile products for parenteral and ocular use.

It is intended that students learn how to produce and control the quality of the dosage forms under study, and to promote:

  • the acquisition and development of research attitudes and reflection,
  • group work and, simultaneously, develop individual leadership and communication skills, as well as critical thinking.

At the end of this course students should be able to recognize the advantages and limitations of the use of the therapeutic dosage forms under study and apply the most recent scientific and technological knowledge in the maximization of their effectiveness.

Syllabus:
  1. SOLUTIONS
    Oral solutions (syrups), nasal, auricular, rectal, vaginal, antiseptic, disinfectant
    Raw materials, manufacturing technology, packaging and quality control
  2. EMULSIONS
    Emulsification and emulsion instability
    Raw materials, manufacturing technology, packaging and quality control
  3. SUSPENSIONS
    Flotation and sedimentation of particles; crystal growth ; redispersibility
    Raw materials, manufacturing technology, packaging and quality control
  4. TOPICAL SEMISOLIDS
    Ointments, pastes, gels, creams, poultices, plasters and foams
    Raw materials, manufacturing technology, packaging and quality control
  5. SUPPOSITORIES AND PESSARIES
    Raw materials, manufacturing technology, packaging and quality control
  6. STERILE DOSAGE FORMS (PARENTERAL AND OPHTHALMIC)
    Raw materials, manufacturing technology, packaging and quality control
    Isotonization
    Sterilization
Suggested Bibliography:
  • Lachman L, Lieberman HA, Kanig JL (eds) (2010) Teoria e Prática na Indústria Farmacêutica, 2ª ed., Fundação Calouste Gulbenkian, Lisboa. ISBN: 9789723109085.
  • Aulton ME, Taylor KMG (ed.) (2017) Aulton's Pharmaceutics: the Design and Manufacture of Medicines, 5th ed., Elsevier. ISBN: 9780702070051.
  • Florence AT, Siepmann J (2009) Modern Pharmaceutics, 5th ed., Informa Healthcare, New York. ISBN: 9781420065701.
  • Jones D (2008) Pharmaceutics: Dosage Forms and Design, Pharmaceutical Press. ISBSN: 9780853697640.
  • Avis KE, Lieberman HA, Lachman L (eds) (2010) Pharmaceutical Dosage Forms: Parenteral Medications Vol. I, II e III, 3rd ed., Marcel Dekker, Inc., New York. ISBN: 9781420086539