Pharmaceutical Technology II
Tecnologia Farmacêutica II
Course code:9494331
Ana Isabel Henriques Dias Fernandes Pinto
Learning outcomes of the curricular unit:
Provide students with the theoretical and practical knowledge adequate to the design, formulation, production and quality control of solutions, emulsions and suspensions, topical semi-solids, vaginal and rectal dosage forms, and the sterile products for parenteral and ocular use.
It is intended that students learn how to produce and control the quality of the dosage forms under study, and to promote:
- the acquisition and development of research attitudes and reflection,
- group work and, simultaneously, develop individual leadership and communication skills, as well as critical thinking.
At the end of this course students should be able to recognize the advantages and limitations of the use of the therapeutic dosage forms under study and apply the most recent scientific and technological knowledge in the maximization of their effectiveness.
Syllabus:
- SOLUTIONS
Oral solutions (syrups), nasal, auricular, rectal, vaginal, antiseptic, disinfectant
Raw materials, manufacturing technology, packaging and quality control - EMULSIONS
Emulsification and emulsion instability
Raw materials, manufacturing technology, packaging and quality control - SUSPENSIONS
Flotation and sedimentation of particles; crystal growth ; redispersibility
Raw materials, manufacturing technology, packaging and quality control - TOPICAL SEMISOLIDS
Ointments, pastes, gels, creams, poultices, plasters and foams
Raw materials, manufacturing technology, packaging and quality control - SUPPOSITORIES AND PESSARIES
Raw materials, manufacturing technology, packaging and quality control - STERILE DOSAGE FORMS (PARENTERAL AND OPHTHALMIC)
Raw materials, manufacturing technology, packaging and quality control
Isotonization
Sterilization
Suggested Bibliography:
- Lachman L, Lieberman HA, Kanig JL (eds) (2010) Teoria e Prática na Indústria Farmacêutica, 2ª ed., Fundação Calouste Gulbenkian, Lisboa. ISBN: 9789723109085.
- Aulton ME, Taylor KMG (ed.) (2017) Aulton's Pharmaceutics: the Design and Manufacture of Medicines, 5th ed., Elsevier. ISBN: 9780702070051.
- Florence AT, Siepmann J (2009) Modern Pharmaceutics, 5th ed., Informa Healthcare, New York. ISBN: 9781420065701.
- Jones D (2008) Pharmaceutics: Dosage Forms and Design, Pharmaceutical Press. ISBSN: 9780853697640.
- Avis KE, Lieberman HA, Lachman L (eds) (2010) Pharmaceutical Dosage Forms: Parenteral Medications Vol. I, II e III, 3rd ed., Marcel Dekker, Inc., New York. ISBN: 9781420086539