Pharmacy

1Organic Chemistry II

Quimica Orgânica II

Course code:9494210

Luísa Maria Lima Gonçalves

Learning outcomes of the curricular unit:

This curricular unit seek the students:

  • To be able to pinpoint the main organic reactions and its mechanisms.
  • To be able to explain the formation of radical species and their mechanisms.
  • To predict and be able to classify the chemical behavior of compounds belonging to the more representative organic functions, namely carbonyl compounds and heterocycles.
  • To develop their capacity to design and implement (skills and safety) of laboratory work.

Competences:

  • Ability to plan and carry out synthesis of simple organic molecules.
  • Ability to apply and integrate knowledge to solve problems.
  • Ability to make decisions.
  • Ability to collect, record, analyze, interpret and report data in the context of organic chemistry.
  • Capabilities that allow lifelong learning programs, independently.
  • Ability to work and team learning.
Syllabus:
  1. REVISIONS ON REACTIVITY OF ORGANIC MOLECULES ( ACIDS AND BASES) AND CHARACTERISTIC REACTION MECHANISMS OF ORGANIC COMPOUNDS
  2. ELECTROPHILIC REACTIONS
    Electrophilic addition to unsaturated carbons.
    Electrophilic addition to conjugated systems.
  3. ELECTROPHILIC AND NUCLEOPHILIC AROMATIC SUBSTITUTION
  4. NUCLEOPHILIC REACTIONS OF CARBONYL GROUPS
    Nucleophilic addition to the carbonyl group.
  5. NUCLEOPHILIC REACTIONS INVOLVING ENOLATE IONS
  6. RADICAL REACTIONS
  7. HETREROCYCLES
Suggested Bibliography:
  • Dewick PM (2006) Essentials of Organic Chemistry for Students of Pharmacy, Medicinal Chemistry and Biological Chemistry. 1st ed., John Wiley & Sons, Ltd, England. ISBN- 13:978-0-470-01665-7 (HB).
  • Vollhard KPC & Schore NE (2015) Organic Chemistry. 5th ed., W.H. Freeman & Co., New York. ISBN 978-1464120275.
  • Solomons TW (2014) Organic Chemistry. 6th ed., John Wiley & Sons, Inc. , New York. ISBN 978-1-118-14790-0.