Drugs of Abuse I

Substâncias de Abuso I

Course code:8059215

Doutora Luísa Maria Lima Gonçalves

Learning outcomes of the curricular unit:

1. List, classify and describe substances of abuse and describe its pharmacokinetics and pharmacodynamics
2. In Lab classes students are expected to learn and apply analytical methodologies aiming at the identification and quantification of substances of abuse, namely
3. Know how to identify a substance of abuse using screening tests and explain the basics of screening tests
4. To be able to explain the analytical techniques, to understand the parameters involved in the selection of the method and to know how to select an analytical strategy for a given scenario
5. To be able to analyze and discuss critically potential techniques for laboratory analysis of substances commonly found
6. Know how to use the computer software related to the equipment
7. Interpret the results in a meaningful and structured way in the context of teamwork

Syllabus:

1. Introduction to substances of abuse.
2. Pharmacokinetics of xenobiotics.
3. Pharmacodynamics.
4. Introduction to substances of abuse
5. Pharmacokinetics of Licit and Illicit Substances of Abuse

Suggested Bibliography:

• Karch SB (2007) Drug abuse handbook. Taylor & Francis Group, CRC Press. ISBN-13: 978-0-8493-1690-6
• Karch SB (2008) Pharmacokinetics and pharmacodynamics of abused drugs, New York: Taylor & Francis Group, LLC. ISBN-13: 978-1-4200-5458-3
• Moffat et al (2004) Clarke’s Analysis of Drugs and Poisons. Vol.1. Pharmaceutical Press. ISBN-10: 0853694737
• Wong RC & Harley YT (2005) Drugs of abuse: body fluid testing. Humana Press Inc.New Jersey. ISBN: 1-58829-435-8
• Zedeck BE & Zedeck MS (2007) Forensic Pharmacology, Infobase Publishing, New York. ISBN: 0791089207