Drugs of Abuse II
Substâncias de Abuso II
Álvaro Augusto Teixeira Lopes
Learning outcomes of the curricular unit:
To provide continuity in the acquisition of knowledge about the pharmacologically active substances which are used for non-medical purposes and of forensic interest started in the previous module. Meet the classification systems for substances of abuse as well as neurochemical mechanisms that characterize the phenomena generally associated with pharmacotoxicity, particularly those involving syndromes of tolerance, dependence and toxicity. Meet monographies of other drugs of abuse. Acquire knowledge about international and national legislation applied to this issue.
On laboratory aspects students will learn basic analytical methodologies for identification and quantification of substances of abuse and familiarization with advanced analytical technology.
It is intended that by the end of this UC students have acquired extensive knowledge in the area of substances of abuse.
- Toxicology of drugs of abuse.
- Monographic Studies.
- Analytical Methodologies of identification and quantification.
- Standards for sampling and analysis.
- Comparative study of abused substances.
- Processing of data.
- Validation and quality control of Clandestine Laboratories.
- New Consumer Indicators of risk assessment.
- Case studies.
- Karch BS (2008) Pharmacokinetics and pharmacodynamics of abused drugs, New York: Taylor & Francis Group, LLC. ISBN: 13: 978-1-4200-5458-3
- Jickells S & Nefrusz A (2008) Clarke’s analytical forensic toxicology, Pharmaceutical Press, London. ISBN: 9780853697053
- Cole MD (2004) The Analysis of controlled substances, WileyBlackwell. ISBN-10: 0471492523
- Birkett DJ (2002) Pharmacokinetics Made Easy, McGraw-Hill. ISBN: 978-007471072-2
- Karch SB (2007) Drug abuse handbook, 2nd ed., Taylor & Francis Group, CRC Press. ISBN-13: 978-0-8493-1690-6