Forensic Molecular Genetics
Genética Molecular Forense
Maria Alexandra Taquenho Maia E Silva
Learning outcomes of the curricular unit:
To understand the analysis of DNA profiles students must be aware of the structure of nucleic acids in particular DNA, genomic organization and genetics, has fundamental forensic proofs. Students must also manage knows carry out the basic techniques, for DNA extraction from different biological sources and succeeds in using the DNA extracted to obtain DNA profiles. Students are encouraged to identify the most appropriate strategy in each situation, for example: the source of biological material, the conservation and initial amount; the type of crime, the number of suspects involved, etc. Pupils must learn to find different sources references, reporting similar cases in order to achieve prepare a final report, coherent, solid that could be used in court.
- Introduction to Molecular Genetics.
- Genome organization and DNA classes.
- DNA and RNA markers.
- DNA analysis and PCR.
- STR, SNP and VNTR.
- Extranuclear genomes.
- Y chromosome.
- Non human DNA.
- Analysis of scientific articles.
- Applications of Forensic genetics.
- Buckleton J, Bright J & Taylor D (2016) Forensic DNA Evidence Interpretation, 2nd ed., CRC press, USA. ISBN: 9781482258899
- Butler J (2011) Advanced Topics in Forensic DNA Typing: Methodology, Academic Press, San Diego, USA. ISBN: 9780123745132
- Butler JM (2005) Forensic DNA Typing: Biology, Technology, and Genetics of STR Markers, 2nd ed., Elsevier Academic Press, San Diego/USA. ISBN: 9780121479527
- Goodwin W, Linacre A & Hadi S (2010) An Introduction to Forensic Genetics, 2nd ed., Wiley, UK. ISBN: 9780470710197
- Rapley R & Whitehouse D (2007) Molecular Forensics, Wiley. ISBN: 9780470024966