Physiological Biochemistry II
Bioquímica Fisiológica II
Course code:9548106
Maria Fernanda de Mesquita
Learning outcomes of the curricular unit:
The aim of this CU is to establish a bridge between several disciplines such as Biochemistry and Physiology. The second objective is learning the molecular functioning of human body and prepare the students for a learning aread oriented towards dental medicine: oral biology.
It is intended to provide students with a critical spirit while teaching the dynamic interdependence between organs and systems.
The CU also aims to teach the following skills: being able to do analysis and synthesis in the preparation and paper presentation. Being able to work in a group. Being able to understand the functioning of the human body
Syllabus:
- Cell signalling by chemical messengers. Endocrine system.
- Macro and micronutrients. Biochemistry of digestion and absorption of nutrients. Regulatory peptides from gut and pancreas.
- Lipoprotein and metabolism.
- Hypothalamic-pituitary system as a key element of hormonal regulation. Hormones and hypothalamic factors involved. Peptide groups and glycoprotein derived from pro-opiomelanocortin as pituitary hormones. Posterior pituitary: ADH and Oxytocin. Thyroid gland. Relevant aspects of the metabolism of iodine. Suprarenal cortex and medulla: synthesis, actions, metabolism and degradation. Sex glands: their diversity in man and woman.
- Metabolic interrelationship. Overview of intermediary metabolism.
Suggested Bibliography:
- Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA (2012) Harper’s Illustrated Biochemistry. 29th ed., Appleton and Lange. ISBN-10: 00717657.
- Greenspan FS, Strewler GJ, (2004) Basic & Clinical Endocrinology. 6 ed., Appleton e Lange. ISBN: 0-8385-0588-0.
- Lieberman M, Marks A (2013) Basic Medical Biochemistry, a clinical approach. 4th ed, Williams and Wilking. ISBN: 978-1-60831.