Human Pathology

Patologia Humana

Course code:9504112

Jorge Celso Dias Correia da Fonseca

Learning outcomes of the curricular unit:

After the Curricular Unit Human Pathology, students must be able to understand and describe:

• The basic mechanisms of cell and tissue lesions;
• Cell death and adaptations mechanisms;
• Basic hemodynamic changes;
• Clinical oncology terminology;
• Basic inflammatory and immunological mechanisms;
• Basic pathophysiology of human organs and systems studied during the Human Pathology Unit.

Additionaly, students must acquire/develop:

• The necessary knowledge to use global understanding of disorders when their professional intervention will be needed;
• A wide knowledge of pathological and clinical terminology;
• Skills to drive the clinical practice according with the pathology and pathophysiology knowledge;
• Skills to understand data from laboratory and other exams according with the pathology and pathophysiology knowledge.

After completing the CU, students must be able to:

• Use a pathological and clinical terminology equal to other health professionals;
• Become an important member of the health teams;
• Drive the clinical practice according with the pathology and pathophysiology knowledge;
• Understand data from laboratory and other exams according with the pathology and pathophysiology knowledge.

Syllabus:

1. Pathology: Basic concepts.
2. Etiology: Physical, Chemical, and Living agents.
3. Cell and tissues: Lesion pathways. Cell death and adaptive pathways. Basic hemodynamic changes.
4. Pathophysiology of fever.
5. Pathophysiology of edema.
6. Pathophysiology of pain.
7. Inflammation and basic Immunology.
8. Introduction to clinical oncology.
9. Introduction to the pathology and pathophysiology of the blood.
10. Introduction to the pathology and pathophysiology of the digestive system.
11. Clinical pathology of the Gut.
12. Clinical pathology of the Liver.
13. Clinical pathology of the Biliary System.
14. Clinical pathology of the exocrine Pancreas.
15. Introduction to the pathology and pathophysiology of the urinary system.
16. Introduction to the pathology and pathophysiology of the endocrine system.
17. Clinical pathology of the Hypophysis gland.
18. Clinical pathology of the Thyroid gland.
19. Clinical pathology of the Suprarenal glands.
20. Diabetes and pathology of the endocrine Pancreas.

Suggested Bibliography:

• McPhee SJ, Lingappa, VR, Ganong WF (2005) Pathophysiology of Disease. An Introduction to Clinical Medicine. 5th ed. McGraw-Hill, New York, EUA. ISBN-10: 007144159X.
• Stevens A, Lowe J (2000) Pathology. Mosby-Year Book, 2nd Edition. ISBN-10: 0723431604 (Stevens A, Lowe J. (2004) Patologia. Editora Manole, Tamboré, Brasil. ISBN-85-204-1267-X).
• Gaw A, Cowan RA, O’Reilly D.StJ, Stewart V, Shepherd J (2008) Clinical Biochemistry. 4th ed. Churchill Livingstone, New York, EUA. ISBN-10: 0443069328