Galenics
Farmácia Galénica
Course code:9494224
Maria Deolinda Ferreira dos Santos Auxtero
Learning outcomes of the curricular unit:
The main goal of Galenics is to provide basic knowledge and skills in the design, production and control of pharmaceutics preparing students for laboratorial practice, in the community pharmacy as well as in the hospital pharmacy.
Students must be able to identify, to define and execute basic pharmaceutical unitary operations, as well as to prepare at a lab scale the different drug dosage forms.
In summary, upon completion of the course, students should be able to:
- Interpret medical prescriptions.
- Use different scientific sources for compounding (Ex, Portuguese Pharmacopeia IX).
- Execute pharmaceutical unit operations in order to prepare different formulations, according to the good laboratory and manufacturing practices.
- Identify the different components of the formulations and their functions.
- Apply general and specific rules for labeling medicines.
- Calculate the final price of the medicine, according to the Portuguese legislation.
Syllabus:
- Introduction to Galenic Pharmacy: terminology, definitions and evolution of concepts.
- Medical Prescription. Magisterial and officinal formulas. Compounding, pharmaceutical dosage form.
- Compounding - legislation.
- Classification of pharmaceutical forms.
- Solid dosage forms.
- Preliminary operations.
- Methods for removal of water.
- Equipment used in drying processes.
- Operations in the most common pharmaceutical preparation of solid dosage forms.
- Powder classification.
- Drying by lyophilization.
- Pharmaceutical solutions.
- Water as solvent.
- Methods to obtain purified water.
- Monographs of the various types of water.
- Other adjuvants of pharmaceutical solutions.
- Dispersed systems: emulsions and suspensions.
- Ointments.
- Primary and secondary packaging. Medication administration auxiliary devices. Posologic measurements.
- Packaging materials - glass, plastic, elastomers and metals.
Suggested Bibliography:
- Aulton ME (2007) Aulton's pharmaceutics: the design and manufacture of medicines. 3rd ed., Edinburgh: Churchill Livingstone. ISBN: 978-443-10108-3.
- Jennings TA (1999) Lyophilization. Introduction and Basic Principles, Interpharm Press. ISBN: 1-57491-081-7.
- Le Hir A., pref. Janot M.-M. (1997) Pharmacie galénique : bonnes pratiques de fabrication des médicaments. 7th ed., Paris: Masson, cop. ISBN: 2-225-85546-6.
- Prista LN, Alves AC, Morgado R (2003) Tecnologia farmacêutica. 6th ed., Lisboa: Fundação Calouste Gulbenkian. ISBN: 972-31-0975-1.
- Rowe RC, Weller PJ, Sheskey PJ (2003) Handbook of pharmaceutical excipients, 4th ed., London: The Pharmaceutical Press. ISBN: 1-58212-022-6.