Study Programmes

Animal Organism I – From Molecule to Cellveterinary MIMV

Organismo Animal I – Da Molédula à célula

Course code: 9847102

Alexandre José Neto Trindade

Learning outcomes of the curricular unit:
  • Understand the internal organization of the cell and evolution of prokaryotic cells and eukaryotic, relating the structure and function of cellular organelles with their molecular structure.
  • Analyze the cell as a unit integrated in a biological system that responds to external stimuli of cellular signaling framed in a tissue.
  • Fundamentals of the various chemical processes that make life possible Cellular Energy from Bioenergetics and Metabolic Biochemistry.
  • Learn the mechanisms of integration and regulation of the various metabolic pathways and recognize its importance in maintaining homeostasis.
  • Acquire knowledge about the scientific method and its application in Veterinary Medicine
Syllabus:
  1. Cells and cellular organization. DNA organization in genes and chromosomes. DNA replication.
  2. Regulation of gene expression. Genetics and epigenetics. Recombinant DNA Technology.
  3. Nucleus. Intracellular component structure and function. Cytoskeleton. Circulation of proteins in the cell.
  4. Glucose Metabolism: Glycolysis, Glycogenolysis
  5. Cellular Respiration: Citric Acid Cycle, Oxidative Phosphorylation, Fatty Acid Oxidation, Amino Acid Oxidation
  6. Glucose Biosynthesis
  7. Lipid metabolism: β-oxidation. Lipid Biosynthesis
  8. Amino Acid Metabolism: Transamination and Oxidative Deamination, Decarboxylation; Amino Acid Carbon Chain Metabolism
  9. Amino Acid Metabolism: Urea Cycle
  10. Molecular biology techniques associated with the study, amplification and / or research of genes and gene mutations
  11. Dialysis Sample Conditioning Techniques
  12. Enzyme analysis techniques
Suggested Bibliography:
  • Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. & Walter, P. (2014) - Molecular Biology of the Cell. 6th edition. New York : Garland Science.
  • David L. Nelson, Michael M. Cox (2021). Lehninger Principles of Biochemistry. Eighth Edition. W.H.FREEMAN & CO LTD

 

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