General and Analytical Chemistry
Química Geral e Analítica
Curse code:9494118
Maria Alexandra Sardinha Bernardo
Learning outcomes of the curricular unit:
Through this course students must acquire the basic knowledge in molecular behavior needed to improve their comprehension on the chemical and physical events. This course is design to include laboratory lessons were students should experience and understand the most common techniques used in the modern chemistry laboratory.
Students must also become familiar with quantitative analytical chemistry calculations and appropriate selection along with the execution of available laboratory procedures.
The knowledge, theoretical and practical, acquired in this unit of study will be the basis in areas of knowledge of pharmaceuticals (eg. organic chemistry, pharmaceutical chemistry, pharmaceutical technology, galenic pharmacy, pharmacognosy and toxicology).
The following competencies should be acquired at the end of this course:
- Laboratory experience.
- Critical and analytical judgment.
- Information managing skills (careful assembly, collection and interpretation of gathered material).
- Skills in handling new problems.
- Proper argument capacities.
- Ability to learn engaging in individual and teamwork.
Syllabus:
- CHEMICAL BONDING
Theories of chemical bonding.
Solubility. - CHEMICAL EQUILIBRIA AND ANALYTICAL TECHNIQUES
Calculations of aqueous solutions pH over titration curves. Acid-base indicators.
Oxidation-reduction and balance sheets.
Standard electrode potential. Nernst equation.
Calculation of potential solution along titration curves. Redox indicators.
Equilibrium solubility and its relation to: the common ion effect, pH and other equilibria in solution. - CHEMICAL LABORATORY
General methodology. Methods of measurement and separation.
Solutions: concentrations, dilutions and units.
Heating and cooling. Reduced pressure. Drying filtration (Darcy's Law). Measuring volumes of liquids and transfer. Boiling point. Melting/freezing. Densities. Absorption of light and Beer-Lambert Law.
Unit operations of separation.
Solid and liquid purification: recrystallization, sublimation, extraction and distillations.
Suggested Bibliography:
- Skoog DA (2014) Fundamentals of analytical chemistry. 9th ed., Belmont, CA : Thomson-Brooks/Cole. ISBN: 9780495558286.
- Chang R (2015) Chemistry: international edition. 12th ed., New York: Lisboa, McGraw-Hill. ISBN: 978-0078021510.
- Reger D (2010) Química: princípios e aplicações. 2nd ed., Lisboa: Fundação Calouste Gulbenkian. ISBN: 972-31-0773-2.