Biochemistry II
Bioquímica II
Curse code:9494211
Maria Fernanda de Mesquita
Learning outcomes of the curricular unit:
The aim of this CU is established a bridge between several disciplines such as Biochemistry and Physiology. The second objective is learning the molecular functioning of human body and prepared the students for diagnose in clinical chemistry.
It is intended to provide students a critical spirit by a dynamic interdependence between organs and systems.
The CU also has the skills:
- Being able to do analysis and synthesis in the preparation and papers presentation.
- Being able to work in the group.
- Being able to understand the functioning of the human body and clinical chemistry.
Syllabus:
- Cell signaling by chemical messengers.
- Vitamins: lipids and water-soluble.
- Biochemistry of digestion and absorption of nutrients.
- Regulatory peptides from gut and pancreas.
- Lipoprotein and their metabolism.
- Endocrine system: Hypothalamic-pituitary system as a key element of hormonal regulation; Thyroid gland and relevant aspects of the metabolism of iodine; Suprarenal cortex and medulla (synthesis, actions, metabolism and degradation); Endocrine pancreas.
- The Biochemistry of diabetes.
- Biomarkers of Atherosclerosis.
- Oncogenesis and tumor markers.
- Exploration laboratory liver function and bile.
- Liver function tests.
Suggested Bibliography:
- Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA (2012) Harper’s Illustrated Biochemistry. 29th ed., Appleton and Lange. ISBN-10: 007176576X.
- Gaw A, Murphy MJ, Cowan RA, Reilly DJ, Stewart MJ, Shepherd J (2008) Clinical Biochemistry. Churchill livingstone. ISBN – 9780443069321.
- Newsholme E & Leech T (2010) Functional Biochemistry in Health and Disease. Wiley-Blackwell. ISBN – 978 0 471 98820 5.
- Gardner D (2008) Basic & Clinical Endocrinology. Mcgraw Hill. ISBN - 978-0-07-144011-0.