Oral Biology

Biologia Oral

Curse code:9548205

Maria Fernanda de Mesquita

Learning outcomes of the curricular unit:

• Develop knowledge, attitudes, and skills previously acquired on other CUs, such as integrating and applying these to the stomatognathic system as a part of the human body.
• Acquiring knowledge on the biological and chemical principles of several clinical aspects of Dentistry.
• Boost the need for ongoing training.
• Grant the student with the basis for scientific evidence based evaluation of papers.
• Superficially approach the use and purpose of lab experience in OB and Dentistry.
• Knowing and understanding the lectured topics, such as the ability to analyse, synthesize, and integrate information.
• Analysing, interpreting, and critical and intervening discussion regarding situations related to the lectured topics.
• Regular analysis of knowledge and seeking additional information in order to correct blind-spots.
• Evaluating papers and integrating this information for improving oral health.
• Understanding the experimental method as the basis of learning and practice in Medicine

Syllabus:

1. Introduction to tissues in the oral cavity:
   Oral cavity model: anatomy, physiology, and function of the structures in the oral cavity;
   Connective and epithelial tissues: collagen, elastine, glycoproteins, proteoglicans, and glicosaminoglicans.
   Cell components: fibroblasts, odontoblasts,osteoclasts ameloblasts, cementoblasts, cementoclasts.
   Biological apatitis.
2. Oral cavity tissues – biology:
   Pulp, dentine, and enamel: composition, formation, and metabolism.
   Periodontium: gum, cementum, periodontal ligament, and alveolar bone;
   Salivary glands: composition and function of saliva;
   Regulating salivary function.
3. Changes in the oral cavity homeosthatics:
   Dental plaque and bacterial plaque: composition, formation, and function;
   Fluoride: pharmacokinetics and pharmacodynamics, toxicity, usage.

Suggested Bibliography:

• Alberts B., Bray D., Lewis J., Raff M, Roberts K. Watson D (1994) Molecular Biology Of The Cell. 3rd ed., Garland Publishing Inc., New York. ISBN- 0-8153-1619-4.
• Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA (2012) Harper’s Illustrated Biochemistry. 29th ed., Appleton and Lange. ISBN-10: 00717657.
• Jenkins GN (1978) The Physiology and Biochemistry of the Mouth. 4th ed., Blackwell Scientific Publications, Oxford. ISBN- 10: 0632001380.
• Thylstrup A. and Fejerskov, O. (1994) Textbook of Clinical Cariology. 2nd ed., Munksgaard, Copenhagen. ISNB- 87-16-10916-3.
• Cole AS, Eastoe JE (1988) Biochemistry and Oral Biology. 4th ed., Wright and Sons. ISBN- 0723608342.