Laboratorial Immunology

Imunologia Laboratorial

Course code:68210

Luciana Maria Gonçalves Da Costa

Learning outcomes of the curricular unit:

At the end of this unit, we expect that the student will be able to:

• Understand the composition and function of the immune system, namely concerned to the basic and general aspects of immune response.
• Know and understand the main mechanisms underlying the modulation of the immune response in physiologic conditions.
• Know the main areas of Immunopathology: Immunodeficiency, Allergy, Infection, Auto-immune diseases and Tumors.
• Understand the multidisciplinary application of Immunology’s study.
• Acquire competencies into the main methods used in the laboratorial study of Immunology, including diagnostics.
• Know how to perform the basic immunological techniques.
• Become familiar with the routine of laboratorial work engaged in an immunology laboratory

Syllabus:

1. Introduction to the study of Immunology. General aspects and multidisciplinary approach.
2. Basic and general concepts about immune system and its functional aspects.
3. Organization of the immune system: cells, organs and systems.
4. Innate and acquired immune response.
5. Immunoregulation and Clinic Immunology: Immunodeficiency, Allergy, Immunology of infection, Auto-immune diseases and Immunology of tumours.
6. Theoretical approach to the experimental techniques to be develop and executed in the laboratory. Interpretation of results in a clinical context.

Suggested Bibliography:

• Abbas AK, Lichtman AH (2014) Basic Immunology- Functions and Disorders of the Immune System, 4th ed., Saunders- Elsivier.
• Arosa F, Cardoso E, Pacheco F, (2012) Fundamentos de Imunologia, 2nd ed., Lidel.
• Janeway C & Travers P (2008) Janeway's Immunobiology, 7th ed, Blackwell Scientific Publications.
• Roitt IM, Delves PJ (2011) Roitt’s Essential Immunology, 12th ed., Blackwell Science