Organic Chemistry

Química Orgânica

Course code:68102

Maria Gabriela Machado de Almeida

Learning outcomes of the curricular unit:

• Use the rules of IUPAC nomenclature of organic compounds for naming and writing structural formulas.
• To know the most relevant organic reactions for biological systems and to preview reaction products.
• To describe the main reaction mechanisms.
• To understand the basic of protein’s structure and to relate their structural properties with biological functions.
• To recognize the basic structures of biological macromolecules and to identify their functional groups; Understand their role in cellular structure and function.
• To be independent in lab settings.
• Search the fundamental relationships resulting from a theoretical perspective and apply it to resolution of practical problems.

Syllabus:

1. Carbon-based compounds.
2. Functional groups.
3. Nomenclature.
4. Isomers.
5. Nucleophilic substitution and elimination reactions.
6. Additions to carbon–carbon double and triple bonds.
7. Carbonyl group reactions: additions and substitutions.
8. Acid-base reactions.
9. Carbohydrates.
10. Lipids.
11. Amino acids, peptides, and proteins.
12. Nucleotides and nucleic acids.

Suggested Bibliography:

• Fox MA & Whitesell JK (2004) Organic Chemistry, 3rd ed., Jones & Bartlett, San Diego
• Morrison R & Boyd R (1997) Química Orgânica, 13rd ed., Calouste Gulbenkian, Lisboa
• Solomons T et al (2013) Organic Chemistry, 11th ed., Wiley & Sons, New York
• Campos L & Mourato M (2002) Nomenclatura dos Compostos Orgânicos, Escolar Ed., Lisboa