Biomedical Lab Sci

Organic Chemistry2

Química Orgânica

Course code:68102

Maria Gabriela Machado de Almeida

Learning outcomes of the curricular unit:
  • Use the rules of IUPAC nomenclature of organic compounds for naming and writing structural formulas.
  • To know the most relevant organic reactions for biological systems and to preview reaction products.
  • To describe the main reaction mechanisms.
  • To understand the basic of protein’s structure and to relate their structural properties with biological functions.
  • To recognize the basic structures of biological macromolecules and to identify their functional groups; Understand their role in cellular structure and function.
  • To be independent in lab settings.
  • Search the fundamental relationships resulting from a theoretical perspective and apply it to resolution of practical problems.
Syllabus:
  1. Carbon-based compounds.
  2. Functional groups.
  3. Nomenclature.
  4. Isomers.
  5. Nucleophilic substitution and elimination reactions.
  6. Additions to carbon–carbon double and triple bonds.
  7. Carbonyl group reactions: additions and substitutions.
  8. Acid-base reactions.
  9. Carbohydrates.
  10. Lipids.
  11. Amino acids, peptides, and proteins.
  12. Nucleotides and nucleic acids.
 
Suggested Bibliography:
  • Fox MA & Whitesell JK (2004) Organic Chemistry, 3rd ed., Jones & Bartlett, San Diego
  • Morrison R & Boyd R (1997) Química Orgânica, 13rd ed., Calouste Gulbenkian, Lisboa
  • Solomons T et al (2013) Organic Chemistry, 11th ed., Wiley & Sons, New York
  • Campos L & Mourato M (2002) Nomenclatura dos Compostos Orgânicos, Escolar Ed., Lisboa