Organic Chemistry II

Quimica Orgânica II

Curse code:9494210

Luísa Maria Lima Gonçalves

Learning outcomes of the curricular unit:

This curricular unit seek the students:

• To recognise the importance of the electrons and its distribution in an organic molecule
• To be able to pinpoint the main organic reactions and its mechanisms
• To be able to explain the formation of radical species and their mechanisms
• To predict and be able to classify the chemical behavior of compounds belonging to the more representative organic functions, namely carbonyl compounds and heterocycles
• To develop their capacity to design and implement (skills and safety) of laboratory work

Competences:

• Ability to plan and carry out synthesis of simple organic molecules
• Ability to apply and integrate knowledge to solve problems
• Ability to make decisions
• Ability to collect, record, analyze, interpret and report data in the context of organic chemistry
• Capabilities that allow lifelong learning programs, independently
• Ability to work and team learning

Syllabus:

1. Concept’s revisions about reactivity of organic molecules ( acids and bases) and characteristic reaction mechanisms of organic compounds
2. Electrophilic reactions
3. Electrophilic addition to unsaturated carbons
4. Electrophilic addition to conjugated systems
5. Electrophilic and nucleophilic aromatic substitution
6. Nucleophilic reactions of carbonyl groups
7. Nucleophilic addition to the carbonyl group
8. Nucleophilic reactions involving enolate ions
9. Radical reactions
10. Hetrerocycles

Suggested Bibliography:

• Dewick, P.M. (2006) “ Essentials of Organic Chemistry for Students of Pharmacy, Medicinal Chemistry and Biological Chemistry”, 1st ed., John Wiley & Sons, Ltd, England. ISBN- 13:978-0-470-01665-7 (HB)
• Vollhard, K.P.C., Schore, N.E. (2003) “Organic Chemistry”, 4th ed., W.H. Freeman & Co., New York. ISBN 0- 7167-4374-4
• Solomons, T.W. (1996) “Organic Chemistry”, 6th ed., John Wiley & Sons, Inc. , New York. ISBN 0-471-01342-0
• Campos, L.S., Mourato, M. (1999) “Nomenclatura dos Compostos Orgânicos”, 2ª ed., Escolar Editora, Lisboa. ISBN 972-592-107-0. 5
• Vogel, A.I., (1994) “Vogel’s Texbook of Practical Organic Chemistry”, 5th ed., Longman Scientific & Technical. ISBN 05-8246-2363
• Becker, H. e tal. (1997) “Organikum Química Orgânica Experimental”, 2nd ed., Fundação Calouste Gulbenkian, Lisboa. ISBN 972-31-0704-x6