Organic Chemistry I
Quimica Orgânica I
Curse code:9494115
Zilda Braga Morais
Learning outcomes of the curricular unit:
This unit contribute to the topics A, C, J, K, L of the Pharmaceutical Act, described in DL 288/2001. Its aim is to provide students with general knowledge of organic compounds.
After having completed this course, the student should be able to:
- Recognize and exemplify mono and polyfunctional organic compounds using IUPAC name or structure
- Characterize molecules according to the polarity. Compare organic molecules for physical constants such as melting and boiling points and solubility in water
- Represent acyclic and cyclic organic molecules in stereochemistry projections. Interpret the potential energy / stability of the various conformations. Distinguish stereoisomers. Perform calculations related to the specific optical rotation
- Characterize the main mechanisms of radical and ionic reaction
- Recognize reactions of nucleophilic substitution, the most common nucleophiles and its mode of action. Distinguish SN1 and SN2 reactions
Syllabus:
- Molecular representations and nomenclature
- Atomic structure and bonding
- Stereochemistry
- Acids and bases
- Reaction mechanisms
- Nucleophilic reactions: nucleophilic substitution
Suggested Bibliography:
- Dewick, P. M. (2006). Essentials of Organic Chemistry: For Students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Wiley. ISBN: 978-0-470-01666-4
- Timberlake K.C. (2014). An Introduction to General, Organic, and Biological Chemistry, 12th Edition, Prentice Hall ed., ISBN-13: 978-0321908445
- Campos L. S. & Mourato M. (2002). Nomenclatura dos Compostos Orgânicos, Escolar Editora, Lisboa. ISBN: 972-592-107-0
- Solomons G. T. & Freyhle C. B. (2012). Química Orgânica 9ª ed. Ed LTC. ISBN: 9788521620334
- Morais Z. B. & Silva P. C .(2004). Exercícios de Estereoquímica em Química Orgânica, Ed. Sílabo, Lisboa. ISBN 972-618-335-9