Galenics
Farmácia Galénica
Curse code:9494224
Maria Deolinda Ferreira dos Santos Auxtero
Learning outcomes of the curricular unit:
Students must be able to identify, to define and execute basic pharmaceutical unitary operations, as well as to prepare at a lab scale the different drug dosage forms. In summary, upon completion of the course, students should be able to:
- Interpret medical prescriptions
- Use different scientific sources for compounding (Ex, Portuguese Pharmacopeia IX)
- Execute pharmaceutical unit operations in order to prepare different formulations, according to the good laboratory and manufacturing practices
- Identify the different components of the formulations and their functions
- Apply general and specific rules for labeling medicines
- Calculate the final price of the medicine, according to the Portuguese legislation
- Identify and classify non active medical devices
Syllabus:
- Rules of the unit course
- Introduction to Galenic Pharmacy: terminology, definitions and evolution of concepts
- Medical Prescription. Magisterial and officinal formulas. Compounding, pharmaceutical dosage form
- Compounding - legislation (Decree No. 594/2004)
- Classification of Pharmaceutical Forms
- Solid Dosage Forms
- Preliminary operations
- Methods for removal of water
- Equipment used in drying processes
- Operations in the most common pharmaceutical preparation of solid dosage forms
- Powder Classification
- Drying by lyophilization
- Pharmaceutical Solutions
- Water as solvent
- Methods to obtain purified water
- Monographs of the various types of water
- Other adjuvants of pharmaceutical solutions
- Dispersed Systems: Emulsions and suspensions
- Ointments
- Primary and secondary packaging. Medication administration auxiliary devices. Posologic measurements
- Packaging materials
Suggested Bibliography:
- Michael E. Aulton (2007) “Aulton´s pharmaceutics: the design and manufacture of medicines”, 3rd ed., Edinburgh: Churchill Livingstone, 717 p. : il. ; 25 cm. ISBN 978-443-10108-3
- Jennings TA (1999) “Lyophilization. Introduction and Basic Principles”.Interpharm Press. ISBN 1-57491-081-7
- Le Hir A. ; pref. Janot M.-M. (1997) “Pharmacie galénique : bonnes pratiques de fabrication des médicaments“, 7th ed., Paris:Masson, cop. ISBN 2-225-85546-6
- Cerezo A., Pires F., Loureiro R (1999) “Dispositivos Médicos Não Activos”.Conselho do Colégio da Especialidade de Farmácia Hospitalar, Lisboa, Ordem dos Farmacêuticos. ISBN 972-96555-4-5
- L. Nogueira Prista...[et al.] (2003) “Tecnologia farmacêutica”, 6ª ed., Lisboa : Fundação Calouste Gulbenkian. 786 p. : il. ; 25 cm. ISBN 972-31-0975-1