Clinical Pharmacology I
Farmacologia Clínica I
Curse code:9548218
Isabel Margarida Pratas Reis Costa
Learning outcomes of the curricular unit:
This curricular unit has the objective of providing students general concepts about drugs in order to allow a safe use and prescription of these drugs. Develop skills that allow:
- To recognize potential adverse effects of medications;
- To recognize situations in which a given drug is indicated or contraindicated;
- To recognize / avoid drug interactions.
In theoretical-practical classes students should develop skills that allow:
- To develop research and selection of information, interpretation and synthesis skills;
- To solve problems and justify their own arguments;
- To make a lifelong self-directed and autonomous learning ;
- To develop written and oral communication of scientific content and teamwork;
- To communicate their knowledge and arguments in a clear and unambiguous way.
Syllabus:
- General concepts in pharmacology: General definitions, nomenclature of drugs; Routes of administration; the general cycle of drugs in the body - absorption, distribution, metabolism, excretion; characteristics of each stage; pharmacokinetic concepts.
- Special populations in pharmacology: Children, pregnant and lactating women and the elderly - physiological changes that affect the pharmacokinetics and drug response.
- Basic pharmacokinetic concepts.
- Pharmacology of anti-infective drugs: antibacterial, antifungals, antivirals.
- Antiseptic and disinfectant drugs.
- Local anaesthetics drugs.
In each pharmacological group will be addressed the following aspects:
Main drugs of each group
Mechanism of action
Main pharmacokinetic characteristics
Main indications and contraindications
Adverse effects
Drug Interactions
Suggested Bibliography:
- Katzung BG (2006) Basic and Clinical Pharmacology. 10th ed., McGraw Hill. ISBN 978-0-0714-5153-6.
- Rang HP, Dale MM, Ritter JM (2007) Farmacologia. 6ª ed., Elsevier. ISBN 978-8-5352-2243-2.
- Guimarães S, Moura D, Silva PS (2006) Terapêutica medicamentosa e suas bases farmacológicas. 5ª ed., Porto Editora, Porto. ISBN 978-9-7200-6029-7.
- Craig CR, Stitzel RE (2004) Modern Pharmacology with Clinical Applications. 6th ed., Lippincott Williams & Wilkins. ISBN: 978-0-7817-3762-3.
- Brunton LL, Chabner BA, Knollmann BC (2010) Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th ed., McGraw-Hill Professional, ISBN: 978-0071624428.